Phage infection, transfection and transformation of <i>Mycobacterium avium</i> complex and <i>Mycobacterium paratuberculosis</i>
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منابع مشابه
Phage infection, transfection and transformation of Mycobacterium avium complex and Mycobacterium paratuberculosis.
Mycobacterium avium complex strains and Mycobacterium paratuberculosis are closely related intracellular pathogens affecting humans and animals. M. avium complex infections are a leading cause of morbidity and mortality in AIDS patients, and M. paratuberculosis is the agent of Johne's disease in ruminants. Genetic manipulation of these micro-organisms would facilitate the understanding of their...
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Mycobacterium avium subsp. paratuberculosis and Mycobacterium avium subsp. avium are antigenically and genetically very similar organisms; however, they differ markedly in their virulence for cattle. We evaluated the capacity of bovine macrophages infected with M. avium subsp. paratuberculosis or M. avium subsp. avium to express major histocompatibility complex (MHC) class I and class II antige...
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Paratuberculosis (John’s disease) is infectious and chronically progressive granulomatous disease which affects domestic and wild ruminants. The causative agent is Mycobacterium avium paratuberculosis (MAP), a slow growing mycobactin dependent acid-fast bacillus. We investigated the detection and frequency of MAP in apparently healthy dromedary and Bactrian camels by insertion...
متن کاملParatuberculosis (Johne’s Disease)
Paratuberculosis (Johne's disease) is a chronic enteritis of ruminants caused by infection with Mycobacterium avium subsp paratuberculosis (Map), a slow growing, Gram-positive, 30 acid-fast bacillus. There are three major strains of this organism; S type (sheep type, Type I), C type (cattle type, Type II) and intermediate type (Type III), which have shown strong host preference in Australia. A ...
متن کاملIn silico design and expression of a novel fusion protein of HBHA and high antigenic region of FAP-P of Mycobacterium avium subsp. paratuberculosis in Pichia pastoris
Mycobacterium avium subsp. paratuberculosis (MAP) is the etiologic agent of Johne's disease in ruminants and there has been a shift in the public health approach to MAP and human diseases like Crohn's disease. The prevention of infection by MAP in ruminants is thought to deter the high impact of economic losses in the level of dairy industry and possible spreading of this pathogen in dairy prod...
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